Background Increased expression of TRPV1 receptors in the airways of chronic cough patients and heightened cough responses to inhaled capsaicin are suggestive of a role for TRPV1 receptors in chronic ...

Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona, USA Correspondence to Dr S Guerra, Arizona Respiratory Center, University of Arizona, 1501 N. Campbell Ave, PO ...

5 The Research Center of Experimental Medicine, Guangzhou Medical University, Guangzhou, Guangdong, China 6 The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China 7 ...

Chronic cough (CC) is common, predominantly affecting middle-aged females. Sufferers experience significantly impaired quality of life (QoL). Cough is associated with increased healthcare costs.

Objective: A study was undertaken to estimate the cost-effectiveness of using continuous positive airway pressure (CPAP) in the management of patients with severe obstructive sleep apnoea/hypopnoea ...

Rationale While cross-sectional studies have shown associations between certain occupational exposures and lower levels of lung function, there was little evidence from population-based studies with ...

The British Thoracic Society (BTS) Home Oxygen Guideline provides detailed evidence-based guidance for the use of home oxygen for patients out of hospital. Although the majority of evidence comes from ...

Background: Mannose-binding lectin (MBL) deficiency has been associated with infections of the respiratory tract and with increased disease severity in cystic fibrosis (CF). The mechanism is uncertain ...

1 Real World Data Science, Medical Evidence, BioPharmaceuticals Medical, AstraZeneca, Cambridge, UK 2 Respiratory Evidence Strategy, BioPharmaceuticals Medical, AstraZeneca, Cambridge, UK 3 Research ...

Background The aim of this study was to estimate the long-term (cost-) effectiveness of smoking cessation interventions for patients with chronic obstructive pulmonary disease (COPD). Methods A ...

Introduction and Objectives The harms of hyperoxia are well recognised in COPD, with recommended peripheral oxygen saturations (SpO2) of 88–92%. Despite this, there is ongoing harm from excessive ...

Correspondence to Professor Sailesh Kotecha, Department of Child Health, Cardiff University School of Medicine, Cardiff, CF14 4XN, UK; kotechas{at}cardiff.ac.uk Rationale Increased outdoor air ...