The region braced for a protracted conflict after Israel’s surprise bombardment of Iran’s nuclear and military sites on Friday killed several top generals and nuclear scientists, and neither side showed any sign of backing down.

Iran’s state news agency IRNA said hundreds of ballistic missiles had been launched in retaliation for Israel’s biggest ever attacks on Iran, blasting Iran’s huge underground nuclear site at Natanz an

President Donald Trump told Reuters in a phone interview on Friday that it was unclear if Iran still has a nuclear program following Israeli strikes on the country. Trump told Reuters the U.S. still has nuclear talks planned with Iran on Sunday but that he is not sure if they will still take place.

The Lebanese militant group Hezbollah was long considered Iran’s first line of defense in case of a war with Israel.